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Chronic Exposure to Cadmium and Antioxidants Does Not Affect the Dynamics of Expanded CAG•CTG Trinucleotide Repeats in a Mouse Cell Culture System of Unstable DNA

More than 30 human disorders are caused by the expansion of simple sequence DNA repeats, among which triplet repeats remain the most frequent. Most trinucleotide repeat expansion disorders affect primarily the nervous system, through mechanisms of neurodysfunction and/or neurodegeneration. While tri...

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Pubblicato in:Front Cell Neurosci
Autori principali: Gomes-Pereira, Mário, Monckton, Darren G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884634/
https://ncbi.nlm.nih.gov/pubmed/33603644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.606331
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