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Chemically induced increases and decreases in the rate of expansion of a CAG·CTG triplet repeat
Somatic mosaicism of repeat length is prominent in repeat expansion disorders such as Huntington disease and myotonic dystrophy. Somatic mosaicism is age-dependent, tissue-specific and expansion-biased, and likely contributes toward the tissue-specificity and progressive nature of the symptoms. We p...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419613/ https://ncbi.nlm.nih.gov/pubmed/15155855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh612 |
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