Ethidium Bromide Modifies The Agarose Electrophoretic Mobility of CAG•CTG Alternative DNA Structures Generated by PCR

The abnormal expansion of unstable simple sequence DNA repeats can cause human disease through a variety of mechanisms, including gene loss-of-function, toxic gain-of-function of the encoded protein and toxicity of the repeat-containing RNA transcript. Disease-associated unstable DNA repeats display...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Gomes-Pereira, Mário, Monckton, Darren G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447772/
https://ncbi.nlm.nih.gov/pubmed/28611596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00153
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