CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes

Nuclear histone deacetylase 4 (HDAC4) represses MEF2-mediated transcription, implicated in the development of heart failure. CaMKII-dependent phosphorylation drives nucleus-to-cytoplasm HDAC4 shuttling, but protein kinase A (PKA) is also linked to HDAC4 translocation. However, the interplay of CaMKI...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Basic Res Cardiol
Asıl Yazarlar: Helmstadter, Kathryn G., Ljubojevic-Holzer, Senka, Wood, Brent M., Taheri, Khanha D., Sedej, Simon, Erickson, Jeffrey R., Bossuyt, Julie, Bers, Donald M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2021
Konular:
Original Contribution
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884572/
https://ncbi.nlm.nih.gov/pubmed/33590335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-021-00850-2
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller