CaMKIIδC Drives Early Adaptive Ca(2+) Change and Late Eccentric Cardiac Hypertrophy

CaMKII (Ca(2+)-Calmodulin dependent protein kinase) δC activation is implicated in pathological progression of heart failure (HF) and CaMKIIδC transgenic mice rapidly develop HF and arrhythmias. However, little is known about early spatio-temporal Ca(2+) handling and CaMKII activation in hypertrophy...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Ljubojevic-Holzer, Senka, Herren, Anthony W., Djalinac, Natasa, Voglhuber, Julia, Morotti, Stefano, Holzer, Michael, Wood, Brent M., Abdellatif, Mahmoud, Matzer, Ingrid, Sacherer, Michael, Radulovic, Snjezana, Wallner, Markus, Ivanov, Milan, Wagner, Stefan, Sossalla, Samuel, von Lewinski, Dirk, Pieske, Burkert, Brown, Joan Heller, Sedej, Simon, Bossuyt, Julie, Bers, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547876/
https://ncbi.nlm.nih.gov/pubmed/32821022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.316947
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