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FRET-based sensor Camui provides new insight into mechanisms of CaMKII activation in intact cardiomyocytes

RATIONALE: Calcium/calmodulin dependent protein kinase II (CaMKII) is a key mediator of intracellular signaling in the heart. However, the tools currently available for assessing dynamic changes in CaMKII localization and activation in living myocytes are limited. OBJECTIVE: Here we use Camui, a nov...

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Detalles Bibliográficos
Main Authors: Erickson, Jeffrey R., Patel, Ruchi, Ferguson, Amanda, Bossuyt, Julie, Bers, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182829/
https://ncbi.nlm.nih.gov/pubmed/21835909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.247148
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