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Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells
PARP-7 (TiPARP) is a mono(ADP-ribosyl) transferase whose protein substrates and biological activities are poorly understood. We observed that PARP7 mRNA levels are lower in ovarian cancer patient samples compared to non-cancerous tissue, but PARP-7 protein nonetheless contributes to several cancer-r...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7884071/ https://ncbi.nlm.nih.gov/pubmed/33475085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60481 |
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