A Selective α7 Nicotinic Acetylcholine Receptor Agonist, PNU-282987, Attenuates ILC2s Activation and Alternaria-Induced Airway Inflammation

BACKGROUND: The anti-inflammatory effect of an α7nAChR agonist, PNU-282987, has previously been explored in the context of inflammatory disease. However, the effects of PNU-282987 on type 2 innate lymphoid cells (ILC2s)-mediated allergic airway inflammation has not yet been established. AIMS: To det...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Yuan, Fang, Jiang, Lili, Li, Qianyang, Sokulsky, Leon, Wanyan, Yuanyuan, Wang, Lingli, Liu, Xiaojie, Zhou, Lujia, Tay, Hock L., Zhang, Guojun, Yang, Ming, Li, Fuguang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2021
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883686/
https://ncbi.nlm.nih.gov/pubmed/33597946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.598165
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