Chargement en cours...

A dual effect of PNU-120596 on α7 nicotinic acetylcholine receptor-channel complexes

PNU-120596 (1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea), a Type-II positive allosteric modulator of α7 nicotinic acetylcholine receptors inhibits α7 desensitization and robustly prolongs openings of α7 channels. However, these effects may render α7 channels more accessible to pos...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kalappa, Bopanna I., Uteshev, Victor V.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839061/
https://ncbi.nlm.nih.gov/pubmed/24036349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2013.08.027
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!