α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Ameliorates Cognitive Impairment Induced by Chronic Intermittent Hypoxia

PURPOSE: Cognitive impairment is an important complication of obstructive sleep apnea (OSA). Chronic intermittent hypoxia (CIH), the main pathophysiological characteristics of OSA, is closely related to cognitive dysfunction and may be mediated by alpha-7 nicotinic acetylcholine receptors (α7nAChR)....

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Bibliographische Detailangaben
Veröffentlicht in:Nat Sci Sleep
Hauptverfasser: Shen, Hui, Meng, Yanling, Liu, Dan, Qin, Zheng, Huang, Hong, Pan, Lei, Wang, Wei, Kang, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2021
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123952/
https://ncbi.nlm.nih.gov/pubmed/34007230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NSS.S296701
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