α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Ameliorates Cognitive Impairment Induced by Chronic Intermittent Hypoxia

PURPOSE: Cognitive impairment is an important complication of obstructive sleep apnea (OSA). Chronic intermittent hypoxia (CIH), the main pathophysiological characteristics of OSA, is closely related to cognitive dysfunction and may be mediated by alpha-7 nicotinic acetylcholine receptors (α7nAChR)....

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Detalhes bibliográficos
Publicado no:Nat Sci Sleep
Main Authors: Shen, Hui, Meng, Yanling, Liu, Dan, Qin, Zheng, Huang, Hong, Pan, Lei, Wang, Wei, Kang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123952/
https://ncbi.nlm.nih.gov/pubmed/34007230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NSS.S296701
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