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Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity

Allergic asthma is a complex and chronic inflammatory disorder that is associated with airway hyperreactivity (AHR) and driven by Th2 cytokine secretion. Type 2 innate lymphoid cells (ILC2s) produce large amounts of Th2 cytokines and contribute to the development of AHR. Here, we show that ILC2s exp...

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Foilsithe in:Nat Commun
Main Authors: Galle-Treger, Lauriane, Suzuki, Yuzo, Patel, Nisheel, Sankaranarayanan, Ishwarya, Aron, Jennifer L., Maazi, Hadi, Chen, Lin, Akbari, Omid
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071851/
https://ncbi.nlm.nih.gov/pubmed/27752043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13202
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