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ICOS:ICOS-Ligand interaction is required for type 2 innate lymphoid cell function, homeostasis and induction of airway hyperreactivity

Allergic asthma is caused by Th2 cell-type cytokines in response to allergen exposure. Type 2 innate lymphoid cells (ILC2s) are a newly identified subset of immune cells that besides Th2 cells contribute to the pathogenesis of asthma by producing copious amount of IL-5 and IL-13 which cause eosinoph...

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Publicado en:Immunity
Main Authors: Maazi, Hadi, Patel, Nisheel, Sankaranarayanan, Ishwarya, Suzuki, Yuzo, Rigas, Diamanda, Soroosh, Pejman, Freeman, Gordon J., Sharpe, Arlene H., Akbari, Omid
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366271/
https://ncbi.nlm.nih.gov/pubmed/25769613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.02.007
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