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Pharmacological inhibition of the mitochondrial Ca(2+) uniporter: relevance for pathophysiology and human therapy
Mitochondrial Ca(2+) uptake has long been considered crucial for meeting the fluctuating energy demands of cells in the heart and other tissues. Increases in mitochondrial matrix [Ca(2+)] drive mitochondrial ATP production via stimulation of Ca(2+)-sensitive dehydrogenases. Mitochondria-targeted sen...
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| Publicat a: | J Mol Cell Cardiol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7880870/ https://ncbi.nlm.nih.gov/pubmed/33035551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.09.014 |
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