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Mitochondrial Ca(2+) Uniporter and CaMKII in heart
The influx of cytosolic Ca(2+) into mitochondria is mediated primarily by the mitochondrial calcium uniporter (MCU)(1), a small-conductance, Ca(2+)-selective channel(2-6). MCU modulates intracellular Ca(2+) transients and regulates ATP production and cell death(1). Recently, Joiner et al. reported t...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476531/ https://ncbi.nlm.nih.gov/pubmed/25254480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13626 |
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