Serum levels of anti-PspA and anti-PspC IgG decrease with age and do not correlate with susceptibility to experimental human pneumococcal colonization

Older adults are at increased risk of pneumococcal disease. This work aims to evaluate whether there is any decrease in serum IgG against variants of the antigens Pneumococcal surface protein A (PspA) and Pneumococcal surface protein C (PspC) in healthy adults with increasing age. Levels of IgG agai...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Araujo, Adriano P., Colichio, Gabriela B. C., Oliveira, Maria Leonor S., German, Esther, Nikolaou, Elissavet, Chen, Tao, Adler, Hugh, Ferreira, Daniela M., Miyaji, Eliane N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880446/
https://ncbi.nlm.nih.gov/pubmed/33577617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247056
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