Serum levels of anti-PspA and anti-PspC IgG decrease with age and do not correlate with susceptibility to experimental human pneumococcal colonization

Older adults are at increased risk of pneumococcal disease. This work aims to evaluate whether there is any decrease in serum IgG against variants of the antigens Pneumococcal surface protein A (PspA) and Pneumococcal surface protein C (PspC) in healthy adults with increasing age. Levels of IgG agai...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Araujo, Adriano P., Colichio, Gabriela B. C., Oliveira, Maria Leonor S., German, Esther, Nikolaou, Elissavet, Chen, Tao, Adler, Hugh, Ferreira, Daniela M., Miyaji, Eliane N.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2021
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880446/
https://ncbi.nlm.nih.gov/pubmed/33577617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247056
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