Sulforaphane promotes C. elegans longevity and healthspan via DAF-16/DAF-2 insulin/IGF-1 signaling

The broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear. We used the C. elegans nematode model and fed the wildtype and 9 mutant strains ±sulforaphane. The lifespan, phenotype, pharyngeal pumping, mob...

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Publicat a:Aging (Albany NY)
Autors principals: Qi, Zhimin, Ji, Huihui, Le, Monika, Li, Hanmei, Wieland, Angela, Bauer, Sonja, Liu, Li, Wink, Michael, Herr, Ingrid
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880325/
https://ncbi.nlm.nih.gov/pubmed/33471780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202512
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