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Molecular mechanism of mureidomycin biosynthesis activated by introduction of an exogenous regulatory gene ssaA into Streptomyces roseosporus

Mureidomycins (MRDs), a group of unique uridyl-peptide antibiotics, exhibit antibacterial activity against the highly refractory pathogen Pseudomonas aeruginosa. Our previous study showed that the cryptic MRD biosynthetic gene cluster (BGC) mrd in Streptomyces roseosporus NRRL 15998 could not be act...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci China Life Sci
Prif Awduron: Liu, Ning, Guan, Hanye, Niu, Guoqing, Jiang, Lingjuan, Li, Yue, Zhang, Jihui, Li, Jine, Tan, Huarong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Science China Press 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880210/
https://ncbi.nlm.nih.gov/pubmed/33580428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11427-020-1892-3
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