Molecular mechanism of mureidomycin biosynthesis activated by introduction of an exogenous regulatory gene ssaA into Streptomyces roseosporus

Mureidomycins (MRDs), a group of unique uridyl-peptide antibiotics, exhibit antibacterial activity against the highly refractory pathogen Pseudomonas aeruginosa. Our previous study showed that the cryptic MRD biosynthetic gene cluster (BGC) mrd in Streptomyces roseosporus NRRL 15998 could not be act...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci China Life Sci
Päätekijät: Liu, Ning, Guan, Hanye, Niu, Guoqing, Jiang, Lingjuan, Li, Yue, Zhang, Jihui, Li, Jine, Tan, Huarong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Science China Press 2021
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880210/
https://ncbi.nlm.nih.gov/pubmed/33580428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11427-020-1892-3
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