PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function

BACKGROUND: Abnormal neovascularization is the most common cause of blindness, and hypoxia alters tissue metabolism, function, and morphology. HIF-1α, the transcriptional activator of VEGF, has intricate mechanisms of nuclear translocation and activation, but its signal termination mechanisms remain...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Dong, Lijie, Li, Wenbo, Lin, Tingting, Liu, Boshi, Hong, Yaru, Zhang, Xiaomin, Li, Xiaorong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879653/
https://ncbi.nlm.nih.gov/pubmed/33573690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00684-w
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