Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension

Pulmonary hypertension (PH) is characterized by increased pulmonary vascular resistance, pulmonary vascular remodeling, and increased pulmonary vascular pressures that often result in right ventricular dysfunction, leading to right heart failure. Evidence suggests that reactive oxygen species (ROS)...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Adesina, Sherry E., Wade, Brandy E., Bijli, Kaiser M., Kang, Bum-Yong, Williams, Clintoria R., Ma, Jing, Go, Young-Mi, Hart, C. Michael, Sutliff, Roy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451594/
https://ncbi.nlm.nih.gov/pubmed/28130258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00258.2016
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