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Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension
Pulmonary hypertension (PH) is characterized by increased pulmonary vascular resistance, pulmonary vascular remodeling, and increased pulmonary vascular pressures that often result in right ventricular dysfunction, leading to right heart failure. Evidence suggests that reactive oxygen species (ROS)...
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| 發表在: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5451594/ https://ncbi.nlm.nih.gov/pubmed/28130258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00258.2016 |
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