Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension

Pulmonary hypertension (PH) is characterized by increased pulmonary vascular resistance, pulmonary vascular remodeling, and increased pulmonary vascular pressures that often result in right ventricular dysfunction, leading to right heart failure. Evidence suggests that reactive oxygen species (ROS)...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Adesina, Sherry E., Wade, Brandy E., Bijli, Kaiser M., Kang, Bum-Yong, Williams, Clintoria R., Ma, Jing, Go, Young-Mi, Hart, C. Michael, Sutliff, Roy L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451594/
https://ncbi.nlm.nih.gov/pubmed/28130258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00258.2016
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