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Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis
Despite a general repression of translation under hypoxia, cells selectively upregulate a set of hypoxia-inducible genes. Results from deep sequencing revealed that Let-7 and miR-103/107 are hypoxia-responsive microRNAs (HRMs) that are strongly induced in vascular endothelial cells. In silico bioinf...
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| Autors principals: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582133/ https://ncbi.nlm.nih.gov/pubmed/23426184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65344 |
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