Double-Stranded RNA Dependent Kinase R Regulates Antibacterial Immunity in Sepsis

Double-stranded RNA dependent kinase R (PKR) is originally identified as an intracellular sensor of viral infection, but its role in bacterial infection remains largely unknown. Here we report that PKR was an important regulator of antibacterial immunity in sepsis. Genetic deletion of PKR or pharmac...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Yang, Yanliang, Xie, Lingli, Zhong, Yanjun, Zhong, Xiaoli, Meng, Ran, Xue, Qianqian, Liang, Fang, Zhao, Kai, Tang, Yiting
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879320/
https://ncbi.nlm.nih.gov/pubmed/33333514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000507932
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