Double-Stranded RNA-Dependent Protein Kinase-Dependent Apoptosis Induction by a Novel Small Compound

The interferon-induced, double-stranded RNA-dependent protein kinase (PKR) can play critical roles in inhibiting virus replication and inducing apoptosis. To develop new agents that may inhibit viral replication or induce apoptosis in cancer cells via the PKR signaling pathway, we screened a chemica...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hu, Wenxian, Hofstetter, Wayne, Wei, Xiaoli, Guo, Wei, Zhou, Yanbin, Pataer, Abujiang, Li, Hong, Fang, Bingliang, Swisher, Stephen G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Pharmacology and Experimental Therapeutics 2009
Pynciau:
Chemotherapy, Antibiotics, and Gene Therapy
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658620/
https://ncbi.nlm.nih.gov/pubmed/19066342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.141754
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