Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells

Microglia have recently been established as key regulators of brain development. However, their role in neuronal subtype specification remains largely unknown. Using three different co-culture setups, we show that microglia-secreted factors enhance dopaminergic differentiation of somatic and induced...

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發表在:Stem Cell Reports
Main Authors: Schmidt, Sissel Ida, Bogetofte, Helle, Ritter, Louise, Agergaard, Jette Bach, Hammerich, Ditte, Kabiljagic, Amina Arslanagic, Wlodarczyk, Agnieszka, Lopez, Silvia Garcia, Sørensen, Mia Dahl, Jørgensen, Mie Lærkegård, Okarmus, Justyna, Serrano, Alberto Martínez, Kristensen, Bjarne Winther, Freude, Kristine, Owens, Trevor, Meyer, Morten
格式: Artigo
語言:Inglês
出版: Elsevier 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878834/
https://ncbi.nlm.nih.gov/pubmed/33482100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.12.011
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