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Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling

INTRODUCTION: CXCR4 and epidermal growth factor receptor (EGFR) represent two major families of receptors, G-protein coupled receptors and receptor tyrosine kinases, with central functions in cancer. While utilizing different upstream signaling molecules, both CXCR4 and EGFR activate kinases ERK and...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: Spinosa, Phillip C., Kinnunen, Patrick C., Humphries, Brock A., Luker, Gary D., Luker, Kathryn E., Linderman, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878609/
https://ncbi.nlm.nih.gov/pubmed/33643466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-020-00640-1
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