Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi‐Ethnic Allele and Copy Number Variant Detection

To develop a novel pharmacogenetic genotyping panel, a multidisciplinary team evaluated available evidence and selected 29 genes implicated in interindividual drug response variability, including 130 sequence variants and additional copy number variants (CNVs). Of the 29 genes, 11 had guidelines pub...

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Gepubliceerd in:Clin Transl Sci
Hoofdauteurs: Scott, Stuart A., Scott, Erick R., Seki, Yoshinori, Chen, Annette J., Wallsten, Richard, Owusu Obeng, Aniwaa, Botton, Mariana R., Cody, Neal, Shi, Huanzhi, Zhao, Geping, Brake, Paul, Nicoletti, Paola, Yang, Yao, Delio, Maria, Shi, Lisong, Kornreich, Ruth, Schadt, Eric E., Edelmann, Lisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877843/
https://ncbi.nlm.nih.gov/pubmed/32931151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12844
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