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Structural variation at the CYP2C locus: Characterization of deletion and duplication alleles
The human CYP2C locus harbors the polymorphic CYP2C18, CYP2C19, CYP2C9 and CYP2C8 genes, and of these, CYP2C19 and CYP2C9 are directly involved in the metabolism of ~15% of all medications. All variant CYP2C19 and CYP2C9 star (*) allele haplotypes currently catalogued by the Pharmacogene Variation (...
Gorde:
| Argitaratua izan da: | Hum Mutat |
|---|---|
| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6810756/ https://ncbi.nlm.nih.gov/pubmed/31260137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23855 |
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