Učitavanje...
Warfarin Pharmacogenetics: CYP2C9 and VKORC1 Genotypes Predict Different Sensitivity and Resistance Frequencies in the Ashkenazi and Sephardi Jewish Populations
Warfarin is a widely used anticoagulant that has a narrow therapeutic range because of both genetic and environmental factors. CYP2C9(∗)2 (p.R144C), CYP2C9(∗)3 (p.I359L), and the VKORC1 promoter (g.-1639G→A) polymorphisms occur frequently in patients who are warfarin “sensitive” and require lower do...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2427171/ https://ncbi.nlm.nih.gov/pubmed/18252229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2007.10.002 |
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