Llwytho...

Carrier Screening for Mucolipidosis Type IV in the American Ashkenazi Jewish Population

Mutations in the MCOLN1 gene cause mucolipidosis type IV (MLIV), a severely debilitating, autosomal recessive, lysosomal storage disorder. Approximately 80% of patients with MLIV are of Ashkenazi Jewish (AJ) descent, and two mutations, IVS3−2A→G and 511del6434, account for >95% of the mutant alle...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Edelmann, Lisa, Dong, Jianli, Desnick, Robert J., Kornreich, Ruth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society of Human Genetics 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC379096/
https://ncbi.nlm.nih.gov/pubmed/11845410
Tagiau: Ychwanegu Tag
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