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Excessive Formation and Stabilization of Dendritic Spine Clusters in the MECP2-Duplication Syndrome Mouse Model of Autism

Autism-associated genetic mutations may perturb the balance between stability and plasticity of synaptic connections in the brain. Here, we report an increase in the formation and stabilization of dendritic spines in the cerebral cortex of the mouse model of MECP2-duplication syndrome, a high-penetr...

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Detalles Bibliográficos
Publicado en:eNeuro
Main Authors: Ash, Ryan Thomas, Park, Jiyoung, Suter, Bernhard, Zoghbi, Huda Yaya, Smirnakis, Stelios Manolis
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877475/
https://ncbi.nlm.nih.gov/pubmed/33168618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0282-20.2020
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