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Excessive Formation and Stabilization of Dendritic Spine Clusters in the MECP2-Duplication Syndrome Mouse Model of Autism

Autism-associated genetic mutations may perturb the balance between stability and plasticity of synaptic connections in the brain. Here, we report an increase in the formation and stabilization of dendritic spines in the cerebral cortex of the mouse model of MECP2-duplication syndrome, a high-penetr...

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Dettagli Bibliografici
Pubblicato in:eNeuro
Autori principali: Ash, Ryan Thomas, Park, Jiyoung, Suter, Bernhard, Zoghbi, Huda Yaya, Smirnakis, Stelios Manolis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877475/
https://ncbi.nlm.nih.gov/pubmed/33168618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0282-20.2020
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