Excessive Formation and Stabilization of Dendritic Spine Clusters in the MECP2-Duplication Syndrome Mouse Model of Autism

Autism-associated genetic mutations may perturb the balance between stability and plasticity of synaptic connections in the brain. Here, we report an increase in the formation and stabilization of dendritic spines in the cerebral cortex of the mouse model of MECP2-duplication syndrome, a high-penetr...

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Bibliographic Details
Published in:eNeuro
Main Authors: Ash, Ryan Thomas, Park, Jiyoung, Suter, Bernhard, Zoghbi, Huda Yaya, Smirnakis, Stelios Manolis
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2021
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Research Article: New Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877475/
https://ncbi.nlm.nih.gov/pubmed/33168618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0282-20.2020
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