Excessive Formation and Stabilization of Dendritic Spine Clusters in the MECP2-Duplication Syndrome Mouse Model of Autism

Autism-associated genetic mutations may perturb the balance between stability and plasticity of synaptic connections in the brain. Here, we report an increase in the formation and stabilization of dendritic spines in the cerebral cortex of the mouse model of MECP2-duplication syndrome, a high-penetr...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Ash, Ryan Thomas, Park, Jiyoung, Suter, Bernhard, Zoghbi, Huda Yaya, Smirnakis, Stelios Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Article: New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877475/
https://ncbi.nlm.nih.gov/pubmed/33168618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0282-20.2020
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