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Excessive Formation and Stabilization of Dendritic Spine Clusters in the MECP2-Duplication Syndrome Mouse Model of Autism

Autism-associated genetic mutations may perturb the balance between stability and plasticity of synaptic connections in the brain. Here, we report an increase in the formation and stabilization of dendritic spines in the cerebral cortex of the mouse model of MECP2-duplication syndrome, a high-penetr...

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Bibliografiske detaljer
Udgivet i:eNeuro
Main Authors: Ash, Ryan Thomas, Park, Jiyoung, Suter, Bernhard, Zoghbi, Huda Yaya, Smirnakis, Stelios Manolis
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877475/
https://ncbi.nlm.nih.gov/pubmed/33168618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0282-20.2020
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