Predictive value of MGMT promoter methylation on the survival of TMZ treated IDH-mutant glioblastoma

OBJECTIVE: O6methylguanine-DNA methyltransferase (MGMT) promoter methylation is a biomarker widely used to predict the sensitivity of IDH-wildtype glioblastoma to temozolomide therapy. Given that the IDH status has critical effects on the survival and epigenetic features of glioblastoma, we aimed to...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Chai, Ruichao, Li, Guanzhang, Liu, Yuqing, Zhang, Kenan, Zhao, Zheng, Wu, Fan, Chang, Yuzhou, Pang, Bo, Li, Jingjun, Li, Yangfang, Jiang, Tao, Wang, Yongzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Compuscript 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877176/
https://ncbi.nlm.nih.gov/pubmed/33628600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2020.0179
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