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PATH-61. A NOVEL ANALYSIS MODEL OF MGMT METHYLATION PYROSEQUENCING OFFERS AN OPTIMAL PREDICTIVE PERFORMANCE IN GLIOMAS

The MGMT methylation is crucial for clinical decision-making in gliomas. MGMT pyrosequencing results were often dichotomized based on a threshold value for the average methylation of several tested CpGs. However, the frequent ‘gray zone’ results of this method immersed physician in a dilemma, and a...

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Publicat a:Neuro Oncol
Autors principals: Chai, Ruichao, Wang, Yongzhi, Liu, Yuqing, Zhang, Kenan, Wu, Fan, Jiang, Tao
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217073/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.715
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