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PATH-61. A NOVEL ANALYSIS MODEL OF MGMT METHYLATION PYROSEQUENCING OFFERS AN OPTIMAL PREDICTIVE PERFORMANCE IN GLIOMAS
The MGMT methylation is crucial for clinical decision-making in gliomas. MGMT pyrosequencing results were often dichotomized based on a threshold value for the average methylation of several tested CpGs. However, the frequent ‘gray zone’ results of this method immersed physician in a dilemma, and a...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217073/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.715 |
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