Simultaneously targeting cancer-associated fibroblasts and angiogenic vessel as a treatment for TNBC

Fibrotic tumor stroma plays an important role in facilitating triple-negative breast cancer (TNBC) progression and chemotherapeutic resistance. We previously reported a rationally designed protein (ProAgio) that targets integrin α(v)β(3) at a novel site. ProAgio induces apoptosis via the integrin. C...

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Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Sharma, Malvika, Turaga, Ravi Chakra, Yuan, Yi, Satyanarayana, Ganesh, Mishra, Falguni, Bian, Zhen, Liu, Wei, Sun, Li, Yang, Jenny, Liu, Zhi-Ren
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876552/
https://ncbi.nlm.nih.gov/pubmed/33561195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200712
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