Overexpression of Smac by an Armed Vesicular Stomatitis Virus Overcomes Tumor Resistance

Despite reports of successful clinical cases, many tumors appear to resist infection by oncolytic viruses (OVs). To circumvent this problem, an armed vesicular stomatitis virus was constructed by inserting a transgene to express Smac/DIABLO during virus infection (VSV-S). Endogenous Smac in HeLa cel...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Oncolytics
Asıl Yazarlar: Li, Weike, Turaga, Ravi Chakra, Li, Xin, Sharma, Malvika, Enadi, Zahra, Dunham Tompkins, Sydney Nicole, Hardy, Kyle Christian, Mishra, Falguni, Tsao, Jun, Liu, Zhi-ren, Fan, Daping, Luo, Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610632/
https://ncbi.nlm.nih.gov/pubmed/31312717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.05.006
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