Modulation of Cancer-Associated Fibrotic Stroma by An Integrin α(v)β(3) Targeting Protein for Pancreatic Cancer Treatment

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is resistant to most therapeutics owing to dense fibrotic stroma orchestrated by cancer-associated pancreatic stellate cells (CAPaSC). CAPaSC also support cancer cell growth, metastasis, and resistance to apoptosis. Currently, there is n...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Mol Gastroenterol Hepatol
Autori principali: Turaga, Ravi Chakra, Sharma, Malvika, Mishra, Falguni, Krasinskas, Alyssa, Yuan, Yi, Yang, Jenny J., Wang, Shiyuan, Liu, Chunfeng, Li, Sun, Liu, Zhi-Ren
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674520/
https://ncbi.nlm.nih.gov/pubmed/32810598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.08.004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi