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Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3

Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. In this study, we show that PRMT5 is overexpressed in...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Shailesh, Harshita, Siveen, Kodappully S., Sif, Saïd
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875925/
https://ncbi.nlm.nih.gov/pubmed/33462997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16260
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