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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/β-catenin and AKT/GSK3β proliferative signaling

Epigenetic regulation by the type II protein arginine methyltransferase, PRMT5, plays an essential role in the control of cancer cell proliferation and tumorigenesis. In this report, we investigate the relationship between PRMT5 and WNT/β-CATENIN as well as AKT/GSK3β proliferative signaling in three...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Chung, Jihyun, Karkhanis, Vrajesh, Baiocchi, Robert A., Sif, Saïd
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514641/
https://ncbi.nlm.nih.gov/pubmed/30885941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007640
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