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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/β-catenin and AKT/GSK3β proliferative signaling

Epigenetic regulation by the type II protein arginine methyltransferase, PRMT5, plays an essential role in the control of cancer cell proliferation and tumorigenesis. In this report, we investigate the relationship between PRMT5 and WNT/β-CATENIN as well as AKT/GSK3β proliferative signaling in three...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chung, Jihyun, Karkhanis, Vrajesh, Baiocchi, Robert A., Sif, Saïd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514641/
https://ncbi.nlm.nih.gov/pubmed/30885941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007640
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