Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/β-catenin and AKT/GSK3β proliferative signaling

Epigenetic regulation by the type II protein arginine methyltransferase, PRMT5, plays an essential role in the control of cancer cell proliferation and tumorigenesis. In this report, we investigate the relationship between PRMT5 and WNT/β-CATENIN as well as AKT/GSK3β proliferative signaling in three...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Chung, Jihyun, Karkhanis, Vrajesh, Baiocchi, Robert A., Sif, Saïd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2019
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514641/
https://ncbi.nlm.nih.gov/pubmed/30885941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007640
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