Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice

The COVID-19 pandemic has revealed that infection with SARS-CoV-2 can result in a wide range of clinical outcomes in humans. An incomplete understanding of immune correlates of protection represents a major barrier to the design of vaccines and therapeutic approaches to prevent infection or limit di...

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Pubblicato in:PLoS Pathog
Autori principali: Graham, Jessica B., Swarts, Jessica L., Leist, Sarah R., Schäfer, Alexandra, Menachery, Vineet D., Gralinski, Lisa E., Jeng, Sophia, Miller, Darla R., Mooney, Michael A., McWeeney, Shannon K., Ferris, Martin T., Pardo-Manuel de Villena, Fernando, Heise, Mark T., Baric, Ralph S., Lund, Jennifer M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875398/
https://ncbi.nlm.nih.gov/pubmed/33513210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009287
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