Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice

The COVID-19 pandemic has revealed that infection with SARS-CoV-2 can result in a wide range of clinical outcomes in humans. An incomplete understanding of immune correlates of protection represents a major barrier to the design of vaccines and therapeutic approaches to prevent infection or limit di...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Graham, Jessica B., Swarts, Jessica L., Leist, Sarah R., Schäfer, Alexandra, Menachery, Vineet D., Gralinski, Lisa E., Jeng, Sophia, Miller, Darla R., Mooney, Michael A., McWeeney, Shannon K., Ferris, Martin T., Pardo-Manuel de Villena, Fernando, Heise, Mark T., Baric, Ralph S., Lund, Jennifer M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875398/
https://ncbi.nlm.nih.gov/pubmed/33513210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009287
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