Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice

The COVID-19 pandemic has revealed that infection with SARS-CoV-2 can result in a wide range of clinical outcomes in humans. An incomplete understanding of immune correlates of protection represents a major barrier to the design of vaccines and therapeutic approaches to prevent infection or limit di...

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Udgivet i:PLoS Pathog
Main Authors: Graham, Jessica B., Swarts, Jessica L., Leist, Sarah R., Schäfer, Alexandra, Menachery, Vineet D., Gralinski, Lisa E., Jeng, Sophia, Miller, Darla R., Mooney, Michael A., McWeeney, Shannon K., Ferris, Martin T., Pardo-Manuel de Villena, Fernando, Heise, Mark T., Baric, Ralph S., Lund, Jennifer M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875398/
https://ncbi.nlm.nih.gov/pubmed/33513210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009287
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