Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Host genetic factors play a fundamental role in regulating humoral immunity to viral infection, including influenza A virus (IAV). Here, we utilize the Collaborative Cross (CC), a mouse genetic reference population, to study genetic regulation of variation in antibody response following IAV infectio...

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Publicado en:Cell Rep
Main Authors: Noll, Kelsey E., Whitmore, Alan C., West, Ande, McCarthy, Mary K., Morrison, Clayton R., Plante, Kenneth S., Hampton, Brea K., Kollmus, Heike, Pilzner, Carolin, Leist, Sarah R., Gralinski, Lisa E., Menachery, Vineet D., Schäfer, Alexandra, Miller, Darla, Shaw, Ginger, Mooney, Michael, McWeeney, Shannon, Pardo-Manuel de Villena, Fernando, Schughart, Klaus, Morrison, Thomas E., Baric, Ralph S., Ferris, Martin T., Heise, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado: The Author(s). 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195006/
https://ncbi.nlm.nih.gov/pubmed/32348764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107587
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