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Different human resting memory CD4+ T cell subsets show similar low inducibility of latent HIV-1 proviruses

The latent reservoir of HIV-1 in resting CD4+ T cells is a major barrier to cure. It is unclear whether the latent reservoir of HIV-1 resides principally in particular subsets of CD4+ T cells, a finding that would have implications for understanding its stability and developing curative therapies. R...

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Publicado en:Sci Transl Med
Main Authors: Kwon, Kyungyoon J., Timmons, Andrew E., Sengupta, Srona, Simonetti, Francesco R., Zhang, Hao, Hoh, Rebecca, Deeks, Steven G., Siliciano, Janet D., Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875249/
https://ncbi.nlm.nih.gov/pubmed/31996465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax6795
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