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HIV persistence: clonal expansion of cells in the latent reservoir

While antiretroviral therapy (ART) can reduce HIV-1 to undetectable levels, the virus generally reappears if treatment is stopped. Resurgence of the virus is due to the reactivation of T cells harboring latent integrated provirus, and recent studies indicate that proliferation of these latently infe...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Kwon, Kyungyoon J., Siliciano, Robert F.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490744/
https://ncbi.nlm.nih.gov/pubmed/28628041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95329
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