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The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence

Combination antiretroviral therapy (ART) for HIV-1 infection reduces plasma virus levels to below the limit of detection of clinical assays. However, even with prolonged suppression of viral replication with ART, viremia rebounds rapidly after treatment interruption. Thus ART is not curative. The pr...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Murray, Alexandra J., Kwon, Kyungyoon J., Farber, Donna L., Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936486/
https://ncbi.nlm.nih.gov/pubmed/27382129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600343
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